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Active ingredient

Clopidogrel 75 mg


  • CLOPEXAGREL belongs to a group of medicines called antiplatelet medicinal products. Platelets are very small structures in the blood, smaller than red or white blood cells, which clump together during blood clotting. By preventing this clumping, antiplatelet medicinal products reduce the chances of blood clots forming (A process called thrombosis).
  • CLOPEXAGREL is taken to prevent blood clots (thrombi) forming in hardened blood vessels (arteries), a process known as atherothrombosis, which can lead to atherothrombotic events (such as stroke, heart attack, or death).
  • You have been prescribed CLOPEXAGREL to help prevent blood clots and reduce the risk of these severe events because:
  •  You have a condition of hardening of arteries (also known as atherosclerosis).
  • You have previously experienced a heart attack, stroke or have a condition known as peripheral arterial disease.
  • You have experienced a severe type of chest pain known as ‘unstable angina’ or ‘myocardial infarction’ (heart attack).
  •  For the treatment of this condition your doctor may have placed a stent in the blocked or narrowed artery to restore effective blood flow.
  •  You should also be given acetylsalicylic acid (a substance present in many medicines used to relieve pain and lower fever as well as to prevent blood clotting) by your doctor.

Dosage and Administration

  • If you have experienced severe chest pain (unstable angina or heart attack), your doctor may give you 300 mg of CLOPEXAGREL (1 tablet of 300 mg or 4 tablets of 75 mg) once at the start of treatment. Then, the usual dose is one 75-mg tablet of CLOPEXAGREL per day to be taken orally with or without food, and at the same time each day.
  •  In addition if you have experienced severe chest pain, your doctor may give you 300 mg of CLOPEXAGREL (4 tablets of 75 mg) at the start of treatment.
  • If a surgery is planned (including dental) you should tell your doctor that you take CLOPEXAGREL.


  • If you are allergic (hypersensitive) to clopidogrel or any of the other ingredients of CLOPEXAGREL.
  • If you have a medical condition that is currently causing bleeding such as a stomach ulcer or bleeding within the brain.
  •  If you suffer from severe liver disease.
  • If you are breast - feeding.
  • If you think any of these apply to you, or if you are in any doubt at all, consult your doctor before taking CLOPEXAGREL.

Side effects

Like all medicines, CLOPEXAGREL can cause side effects; the most common side effect reported with CLOPEXAGREL is bleeding such as bruising, haematoma, nose bleed, blood in the urine. Bleeding in the stomach or bowels, in a small number of cases, bleeding in the eye, inside the head, the lung or the joints has also been reported.
The Other side effects reported with CLOPEXAGREL are:
• Diarrhoea, abdominal pain, constipation, vomiting, nausea, indigestion or heartburn, inflammation in oral lining (stomatitis).
• Vertigo, Headache, decrease in blood pressure, confusion, hallucinations.
• Skin disorders such as: rashes and itching, swelling in the mouth, blisters of the skins, generalised allergic reactions.
• Joint pain, muscular pain, fever, taste disorders.
• Breathing difficulties sometimes associated with cough.

Drug Interaction

  • Some other medicines may influence the use of CLOPEXAGREL or vice versa.
  •  Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
  • The use of oral anticoagulants (medicines used to reduce blood clotting) with CLOPEXAGREL is not recommended.
  • You should specifically tell your doctor if you take a non-steroidal anti-inflammatory drug, usually used to treat painful and/or inflammatory conditions of muscle or joints, or if you take heparin or any other medicine used to reduce blood clotting, or if you take a proton pump inhibitor (e.g. omeprazole) for upset stomach.
  • If you have experienced severe chest pain (unstable angina or heart attack), you may be prescribed CLOPEXAGREL in combination with acetylsalicylic acid, a substance present in many medicines used to relieve pain and lower fever.
    An occasional use of acetylsalicylic acid (no more than 1,000 mg in any 24 hour period) should generally not cause
    a problem, but prolonged use in other circumstances should be discussed with your doctor.

Pregnancy and Lactation

• If you are pregnant or suspect that you are pregnant, you should tell your doctor or your pharmacist before taking CLOPEXAGREL.
• If you become pregnant while taking CLOPEXAGREL, consult your doctor immediately. 
• If you are breast-feeding, you should not take CLOPEXAGREL.

Warning and Precaution

  • If you cut or injure yourself, it may take longer than usual for bleeding to stop. This is linked to the way your medicine works as it prevents the ability of blood clots to form. For minor cuts and injuries e.g. Shaving, this is usually of no concern. However, if you are concerned by your bleeding, you should contact your doctor straightaway.
  • If you notice any side effects not listed in this leaflet, please inform your doctor or pharmacist.

Package and Storage

  • Carton box of three strips with 60 tablets.
  •  Store at temperature not exceeding 30 Cº

Mother Company

Manufactured by Marcyrl